Title of article :
Efficient synthesis of pentasubstituted pyrroles via one-pot reactions of arylamines, acetylenedicarboxylates, and 3-phenacylideneoxindoles
Author/Authors :
Ying Han، نويسنده , , Yan Sun، نويسنده , , Jing Sun، نويسنده , , Chao-Guo Yan، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
An efficient synthetic method for the pentasubstituted pyrroles was successfully developed via the one-pot domino reactions of arylamines, acetylenedicarboxylates, and 3-phenacylideneoxindoles. The reaction mechanism involved the sequential Michael addition and ring closure of the in situ generated β-active enamino ester.
Keywords :
Pyrrole , domino reaction , Heterocycle , Isatin , Electron-deficient alkyne , One-pot reaction
Journal title :
Tetrahedron
Journal title :
Tetrahedron
