Title of article :
β-Lactam-synthon-interceded diastereoselective synthesis of functionally enriched thioxo-imidazolidines, imidazolidin-2-ones, piperazine-5,6-diones and 4,5-dihydroimidazoles
Author/Authors :
Vishu Mehra، نويسنده , , Pardeep Singh، نويسنده , , Vipan Kumar، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
The manuscript explicates simple and convenient protocols for the diastereoselective synthesis of functionally decorated thioxo-imidazolidines, imidazolidin-2-ones, piperazine-5,6-diones and 4,5-dihydroimidazoles using β-lactam synthon approach with an extension towards one-pot synthesis. Since the developed methodology does not employ either the use of Lewis acid conditions or Pd-catalyzed customary procedures, the developed route can be easily modulated for the synthesis of functionalized imidazoles with acid-sensitive functionalities and do not suffer from typical intricacies associated with conventional methods.
Keywords :
4 , ?-Lactam synthon approach , Thioxo-imidazolines , 5-Dihydroimidazoles , Imidazolidine-2-ones , Piperazine-5 , 6-diones
Journal title :
Tetrahedron
Journal title :
Tetrahedron