Title of article :
Heterocyclization of N-(1-chloro-2,2,2-trifluoroethylidene)carbamates with β-enaminoesters—a novel synthetic strategy to functionalized trifluoromethylated pyrimidines
Author/Authors :
Volodymyr A. Sukach، نويسنده , , Viktor M. Tkachuk، نويسنده , , Eduard B. Rusanov، نويسنده , , Gerd-Volker R?schenthaler، نويسنده , , Mykhaylo V. Vovk، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
A novel synthetic strategy to 4-trifluoromethyl substituted 2-oxo-1,2-dihydropyrimidine-5-carboxylates has been developed based on the cyclocondensation of β-enaminoesters with N-(1-chloro-2,2,2-trifluoroethylidene)carbamates.
Keywords :
N-(1-Chloro-2 , 2-trifluoroethylidene)carbamates , Pyrimidines , 2 , Enamines , trifluoromethyl group , Heterocyclization
Journal title :
Tetrahedron
Journal title :
Tetrahedron