Title of article :
Synthesis of Functionalized Cyclopentane for Pactamycin, a Potent Antitumor Antibiotic
Author/Authors :
Nishikawa، Toshio نويسنده , , Tsujimoto، Takashi نويسنده , , Isobe، Minoru نويسنده , , Urabe، Daisuke نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
A tricyclic compound including a cyclopentane structure for pactamycin, an antitumor antibiotic, was constructed by Overman rearrangement and Pauson-Khand cyclization as key steps starting from diacetone-D-glucose.
Keywords :
Overman , Rearrangement , Pauson-Khand reaction , pactamycin , natural products , antibiotics
