First Total Synthesis of Caminoside A, an Antimicrobial Glycolipid from Sponge

Caminoside A, a novel antimicrobial tetrasaccharide glycolipid from the marine sponge Caminus sphaeroconia, which represents the first bacterial type III secretion inhibitor, is synthesized in a total of 57 steps starting from D-glucose, D-galactose, L-rhamnose, and 9-decenal.