Title of article
Ligand promoted and controlled palladium-catalyzed intramolecular Heck reaction of homoallyl alcohols: a facile synthesis of cyclopentaannulated quinolines
Author/Authors
Radhey M. Singh، نويسنده , , Atish Chandra، نويسنده , , Neha Sharma، نويسنده , , Bhawana Singh، نويسنده , , Ritush Kumar، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2012
Pages
5
From page
9206
To page
9210
Abstract
Bidentate phosphine ligands in palladium-catalyzed intramolecular Heck reactions of 2-chloroquinolin-3-yl-(1-homoallyl)alcohols are described to afford facile synthesis of 3-methylene-2,3-dihydro-1H-cyclopenta[b]quinolines in improved yields. We further observed using bulky aromatic phosphine ligand in Pd-catalyzed intermolecular Heck coupling reaction at olefinic centers with iodobenzene also favored exclusively Heck products in excellent yield.
Keywords
Ligand promoted , palladium-catalyzed , Heck cyclization , Quinoline , homoallyl alcohol
Journal title
Tetrahedron
Serial Year
2012
Journal title
Tetrahedron
Record number
1105096
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