Author/Authors :
Qing-He Gao، نويسنده , , Zhuan Fei، نويسنده , , Yan-Ping Zhu، نويسنده , , Mi Lian، نويسنده , , Feng-Cheng Jia، نويسنده , , Mei-Cai Liu، نويسنده , , Neng-Fang She، نويسنده , , An-Xin Wu، نويسنده ,
Abstract :
An I2-promoted sp3 C–H functionalization has been developed for the synthesis of 2,5-disubstituted oxazoles from easily available methyl ketones and benzylamines without any metal and peroxide catalyst. This domino oxidative cyclization process involves the cleavage of C–H bond and the formation of C–N, C–O bonds.
Keywords :
I2-promoted , sp3 C–H functionalization , Domino oxidative cyclization , oxazoles
