Title of article :
Efficient synthesis of novel benzo[b][1,8]naphthyridin-4(1H)-ones and pyrido[2,3-b]quinoxalin-4(1H)-ones from alkynones and primary amines
Author/Authors :
Viktor O. Iaroshenko، نويسنده , , Muhammad Zahid، نويسنده , , Satenik Mkrtchyan، نويسنده , , Ashot Gevorgyan، نويسنده , , Kai Altenburger، نويسنده , , Ingo Knepper، نويسنده , , Alexander Villinger، نويسنده , , Vyacheslav Ya Sosnovskikh، نويسنده , , Peter Langer، نويسنده ,
Abstract :
An efficient palladium-catalyzed cyclization of o-chlorohetaryl ynones with aliphatic and aromatic primary amines represents a simple access to a wide range of benzo[b][1,8]naphthyridin-4(1H)-one and pyrido[2,3-b]quinoxalin-4(1H)-one derivatives in good to excellent yields.
Keywords :
o-Chlorohetaryl ynones , Amines , Palladium-catalyzed cyclization , 8]naphthyridin-4(1H)-ones , 3-b]quinoxalin-4(1H)-ones