Title of article :
Diastereoselective Tandem Michael Additions of Indoles to 3-Nitrocoumarin Derivatives and TMethyl Vinyl Ketone
Author/Authors :
Ye، Meng-Chun نويسنده , , Tang، Yong نويسنده , , Yang، Yao-Yu نويسنده , , Sun، Xiu-Li نويسنده , , Ma، Zhi نويسنده , , Qin، Wei-Min نويسنده ,
Abstract :
Tandem Michael additions of indole derivatives to 3-nitrocoumarins 2, followed by MVK, in one pot, has been developed for the synthesis of multi-functionalized 3,4-dihydrocoumarins bearing a quaternary stereocenter. The reaction proceeds with high diastereoselectivities in good to excellent yields
Keywords :
quinolizidines , cascade reactions , pyrrolizidines , indolizidines
Journal title :
Astroparticle Physics
