Title of article
A domino amino-lactonisation of arylidene pyruvic acids (APAs) by amines in aqueous media
Author/Authors
Morteza Shiri، نويسنده , , Majid M. Heravi، نويسنده , , Bita Soleymanifard، نويسنده , , Hendrik G. Kruger، نويسنده , , Mohammad Ali Zolfigol، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
7
From page
3257
To page
3263
Abstract
The aqueous reaction of arylidene pyruvic acids (APAs) with arylamines or urea under refluxing conditions leading to the formation of 3-(amino)-5-aryl-furan-2(5H)-one, without catalyst, is described. Also (E)-4-(4-chlorophenyl)-2-oxobut-3-enoic acid reacts with 1,2-phenylenediamine to form (E)-3-(4-chlorostyryl)quinoxalin-2(1H)-one under the same conditions. Excellent yields were observed after filtration of the product and washing with brine solution.
Keywords
cascade reaction , arylidene pyruvic acids , Lactone , Cyclisation , Aqueous media
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1105666
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