Title of article :
Synthesis of pyrazoles with fluorinated side-chain by cyclization of fluoroalkylated triketides
Author/Authors :
Willi Desens، نويسنده , , Marleen Winterberg، نويسنده , , Stefan Büttner، نويسنده , , Dirk Michalik، نويسنده , , Ashot S. Saghyan، نويسنده , , Alexander Villinger، نويسنده , , Christine Fischer، نويسنده , , Peter Langer، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
The cyclization of fluoroalkylated 3,5-dioxoesters with hydrazines, carried out in glacial acetic acid, afforded pyrazines with fluoroalkylated side-chain. The cyclization of 3,5-dioxoesters with hydroxylamine afforded hydroxylated fluoroalkylated dihydroisoxazoles. All reactions proceeded with good to very good regioselectivity.
Keywords :
Cyclizations , Dianions , Tautomerism , organofluorine compounds , 1 , 3 , 5-Tricarbonyl compounds
Journal title :
Tetrahedron
Journal title :
Tetrahedron
