Author/Authors :
Keiko Kumagai، نويسنده , , Kazuyasu Kawashima، نويسنده , , Mai Akakabe، نويسنده , , Masayuki Tsuda، نويسنده , , Takamasa Abe، نويسنده , , Masashi Tsuda، نويسنده ,
Abstract :
15N-Choline-d13 was synthesized as a new biomarker for dynamic nuclear polarization, and the lifetime of the polarized signal governed by the spin–lattice relaxation time T1 was measured. 15N-Choline-d13 exhibited a T1 that was over twice as long as that of 15N-choline, and the hyperpolarized 15N signal could be observed for 1 h.