Title of article :
Na2S2O4-Promoted Radical Addition Reaction of Perfluoroalkyl Iodides with Allenes and the TPd(0) -Catalyzed Stereoselective Sonogashira Coupling
Author/Authors :
Ma، Shengming نويسنده , , Alcohol، eaction of Addition Products with TPropargyl نويسنده , , Ma، Zhichao نويسنده ,
Abstract :
A Na2S2O4-promoted radical addition reaction of perfluoroalkyl iodides with allenes affording 1-perfluoroalkyl-2-alken-2-yl iodides 3 in 52-69% yields has been developed. Kinetic resolution of the Z\E mixture via the Pd(0)-catalyzed Sonogashira coupling reaction was applied to prepare pure vinylic iodides (Z)-3 and the related coupling products (E)-4 up to 98:2 E\Z ratio
Keywords :
cascade reactions , pyrrolizidines , indolizidines , quinolizidines
Journal title :
Astroparticle Physics
