Title of article :
Synthesis of [1,2,3]-triazolo[1,5-a][1,4]benzodiazepines via an unprecedented one-pot Cu-catalyzed azidation–cyclization reaction
Author/Authors :
Geert Hooyberghs، نويسنده , , Hendrik De Coster، نويسنده , , Dipak D. Vachhani، نويسنده , , Denis S. Ermolatʹev، نويسنده , , Erik V. Van der Eycken، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
A novel three-step approach leading to [1,2,3]-triazolo[1,5-a][1,4]benzodiazepines in moderate to good yields has been developed. The key step is an unprecedented one-pot Cu-catalyzed azidation–cyclization reaction of ortho-bromobenzylpropargylamines.
Keywords :
Medium-sized ring , Tandem reaction , Benzodiazepine
Journal title :
Tetrahedron
Journal title :
Tetrahedron
