Author/Authors :
Jun Li، نويسنده , , Chunfang Zhang، نويسنده , , Ze-Zhong Ming، نويسنده , , Ge-Fei Hao، نويسنده , , Wen-Chao Yang، نويسنده , , Guangfu Yang، نويسنده ,
Abstract :
A novel coumarin-derived fluorescent probe, FCP, was designed for Zn2+ quantification based on the photo-induced electron transfer (PET) mechanism. This probe selectively and sensitively detects Zn2+ in aqueous solution with wide pH range. Large fluorescence enhancement (13-fold) was observed upon the addition of Zn2+. FCP also displays excellent cell permeability in HeLa cell model and very low cytotoxicity to HEK-293 cell model.
