Title of article :
A Three-Component Synthesis of (1,3-Oxazol-2-yl)-1,2dihydro(iso)quinoline and its further Structural Diversifications
Author/Authors :
Zhu، Jieping نويسنده , , Tron، Gian Cesare نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
A Reissert-type three-component synthesis of 1,3-oxazol-2-yl-1,2dihydro(iso)quinoline is developed using (alpha)-isocyano (beta)-phenyl propionamide as an isonitrile input. The structure of this multicomponent adduct is further diversified taking advantage of the rich chemistry of oxazole.
Keywords :
isocyanide , multicomponent reaction , Reissert reaction , Ugi reaction , isonitrile , aminooxazole , isoquinoline
