Title of article :
Microwave Assisted Suzuki Reactions for the Preparation of the Antifungal 3-Aryl-5-methyl-2,5-dihydrofuran-2-ones
Author/Authors :
Mathews، Christopher J. نويسنده , , Taylor، John نويسنده , , Tyte، Melloney J. نويسنده , , Worthington، Paul A. نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
The Suzuki cross-coupling reaction of arylboronic acids with a bromofuranone has been developed to prepare a series of substituted 2,5dihydrofuran-2-ones related to the fungal metabolite, incrustoporin. A protocol of microwave heating was introduced to improve synthesis throughput.
Keywords :
Palladium , antifungal compounds , arylations , catalysis , microwave heating , cross-coupling
