Title of article :
Cationic dirhodium carboxylate-catalyzed synthesis of dihydropyrimidones from propargyl ureas
Author/Authors :
Miao Yang، نويسنده , , Shannon J. Odelberg، نويسنده , , Zongzhong Tong، نويسنده , , Dean Y. Li، نويسنده , , Ryan E. Looper، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
Cationic Rh(II) complexes are able to catalyze the regioselective hydroamination of propargyl ureas in a 6-endo fashion. This transformation permits access to interesting substitution patterns of dihydropyrimidines, which have found use as nucleotide exchange factor inhibitors.
Keywords :
Dihydropyrimidone , Heterocycle , rhodium catalysis , ARF 6 , Hydroamination
Journal title :
Tetrahedron
Journal title :
Tetrahedron
