• Title of article

    Cationic dirhodium carboxylate-catalyzed synthesis of dihydropyrimidones from propargyl ureas

  • Author/Authors

    Miao Yang، نويسنده , , Shannon J. Odelberg، نويسنده , , Zongzhong Tong، نويسنده , , Dean Y. Li، نويسنده , , Ryan E. Looper، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2013
  • Pages
    7
  • From page
    5744
  • To page
    5750
  • Abstract
    Cationic Rh(II) complexes are able to catalyze the regioselective hydroamination of propargyl ureas in a 6-endo fashion. This transformation permits access to interesting substitution patterns of dihydropyrimidines, which have found use as nucleotide exchange factor inhibitors.
  • Keywords
    Dihydropyrimidone , Heterocycle , rhodium catalysis , ARF 6 , Hydroamination
  • Journal title
    Tetrahedron
  • Serial Year
    2013
  • Journal title
    Tetrahedron
  • Record number

    1105963