Author/Authors :
Run-Lin Li، نويسنده , , Gong-Qing Liu، نويسنده , , Wei Li، نويسنده , , Yu-Mei Wang، نويسنده , , Lin Li، نويسنده , , Lili Duan، نويسنده , , Yueming Li، نويسنده ,
Abstract :
3-Chloropiperidine compounds were obtained via Cu(II)-promoted one-pot intramolecular chloroamination of N-benzyl-4-penten-1-amines and subsequent rearrangement. The reaction conditions leading to this skeleton were studied, and the structure of the product was confirmed by NMR as well as X-ray diffraction experiments.
Keywords :
2-Chloromethylpyrrolidine , 3-Chloropiperidine , N-Benzyl-4-penten-1-amine , Copper chloride , Chloroamination
