Title of article
Diastereoselective and one-pot synthesis of trans-isoquinolonic acids via three-component condensation of homophthalic anhydride, aldehydes, and ammonium acetate catalyzed by aspartic acid
Author/Authors
Arash Ghorbani-Choghamarani، نويسنده , , Maryam Hajjami، نويسنده , , Masoomeh Norouzi، نويسنده , , Yunes Abbasityula، نويسنده , , Vaclav Eigner، نويسنده , , Michal Dusek، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
6541
To page
6544
Abstract
Aspartic acid has been developed as a versatile and highly efficient organocatalyst for the three component combination of homophthalic anhydride, aldehydes, and ammonium acetate to afford trans-isoquinolonic acids. The reactions were carried out in acetonitrile under reflux conditions. Aspartic acid as an efficient organocatalyst exhibits dramatically improved diastereoselectivity compared with previously reported catalysts for this synthetic strategy.
Keywords
Isoquinolonic acid , Diastereoselective , Aldehyde , Homophthalic anhydride , ammonium acetate
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1106059
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