Title of article :
Total synthesis of penmacric acids via an intermolecular radical addition reaction
Author/Authors :
Masafumi Ueda، نويسنده , , Ayako Ono، نويسنده , , Dai Nakao، نويسنده , , Kenji Matsuno، نويسنده , , Takeaki Naito، نويسنده , , Okiko Miyata، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
The total syntheses of penmacric acid and its three stereoisomers were accomplished through the intermolecular radical addition reaction of the 4-pyrrolidyl radical derived from trans-4-hydroxy-l-proline. Furthermore, 1′,3-diepi-penmacric acid was synthesized stereoselectively via double stereoinduction in the radical reaction.
Keywords :
Penmacric acid , radical reaction , Total synthesis , Amino acid
Journal title :
Tetrahedron
Journal title :
Tetrahedron