Title of article :
Cobalt-Mediated Regioselective Synthesis of Substituted Tetrahydroquinolines [1]
Author/Authors :
Groth، Ulrich نويسنده , , Huhn، Thomas نويسنده , , Kesenheimer، Christian نويسنده , , Kalogerakis، Aris نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
A regioselective synthesis of polycyclic substituted pyridines is reported. Key step is the cobalt-catalyzed intramolecular cyclization of diynenitriles, tethered by a silicon oxygen bond. Subsequent opening of the Si-O ring led then to the related tetrahydroquinolines.
Keywords :
Cobalt , Cycloaddition , Quinolines , pyridines , catalysis , Ergot Alkaloids
