Highly efficient asymmetric-axle-supported N–O amides in enantioselective hydrosilylation of ketimines with trichlorosilane

A novel asymmetric-axle-supported chiral N–O amide was synthesized and used in catalytic enantioselective hydrosilylation of N-aryl ketimines with HSiCl3 at room temperature instead of the typical −20 °C. High conversion yield and high enantioselectivity up to 96% were observed.