Author/Authors :
Liang Zhang، نويسنده , , Xinjin Li، نويسنده , , Zhongwei Wang، نويسنده , , Jingwei Zhao، نويسنده , , Jinjin Wang، نويسنده , , Jianwei Han، نويسنده , , Shizheng Zhu، نويسنده ,
Abstract :
An efficient and straightforward nucleophilic substitution reaction between 2-(trifluoromethyl)-2-hydroxy-2H-chromenes and various silyl enol ethers promoted by Lewis acid has been studied. A series of novel 4-functionalized-2-trifluoromethyl-3-ethoxycarbonyl-4H-chromenes were prepared in good yields under mild conditions.
Keywords :
chromene , Trifluoromethyl , silyl enol ethers , Nucleophilic substitution , Lewis acid
