Author/Authors :
Shashikant M. Patil، نويسنده , , Sarang Kulkarni، نويسنده , , Malcolm Mascarenhas، نويسنده , , Rajiv Sharma، نويسنده , , S. Mohana Roopan، نويسنده , , Abhijit Roychowdhury، نويسنده ,
Abstract :
A practical and metal free method for methylthiolation of imidazo[1,2-a]pyridines and other imidazo-fused heterocycles using DMSO–POCl3 complex is reported. The reactions are carried out at room temperature that give the corresponding methylthiolated products in good to excellent yield. Further, its application to indole has been demonstrated.