Title of article
Total synthesis of (+)-azimine via diastereoselective aminopalladation
Author/Authors
Yuji Kurogome، نويسنده , , Masaya Kogiso، نويسنده , , Kok Kong Looi، نويسنده , , Yasunao Hattori، نويسنده , , Hiroyuki Konno، نويسنده , , Mitsuru Hirota، نويسنده , , Hidefumi Makabe، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
8349
To page
8352
Abstract
The aminopalladation of amino allylic alcohol using Cl2Pd(MeCN)2 in CH2Cl2 gave the 2,6-disubstituted piperidine with excellent diastereoselectivity. This compound was successfully converted into (+)-azimine (1) using cross-metathesis and Shiina macrolactonization.
Keywords
Aminopalladation , Alkaloids , piperidine , Natural product
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1106266
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