Title of article
The triflic acid-mediated cyclisation of N-benzylcinnamanilides
Author/Authors
Frank D. King، نويسنده , , Stephen Caddick، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
10
From page
8592
To page
8601
Abstract
N-Benzylcinnamanilides cyclise with triflic acid to form 1-benzyl-4-aryl-2,4-dihydro-1H-quinolin-2-ones and 2,5-diaryl-benzazepin-3-ones. The product ratio is determined by the preferred orientation of the amide and by the electronics of the substituents. With ortho-substituted anilides, N-debenzylation also occurs to give 4-aryl-2,4-dihydro-1H-quinoline-2-ones.
Keywords
Triflic acid , 2 , 5-Diaryl-benzazepin-3-ones , carbocations , 4-Aryl-2 , 4-dihydro-1H-quinolin-2-ones , intramolecular cyclisation
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1106297
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