Author/Authors :
Jae Hoon Choi، نويسنده , , Miyuki Yoshida، نويسنده , , Takayuki Kanda and Tomohiro Suzuki ، نويسنده , , Etsuko Harada، نويسنده , , Mitsuo Kawade، نويسنده , , Kazunaga Yazawa، نويسنده , , Sogo Nishimoto، نويسنده , , Hirofumi Hirai، نويسنده , , Hirokazu Kawagishi، نويسنده ,
Abstract :
A novel sphingosine, 1,2-diacetylsphingosine (1), was isolated from the edible mushroom Grifola gargal. The structure of 1 was determined by the interpretation of spectroscopic data. Compound 1 suppressed the formation of osteoclast without toxicity.
Keywords :
Sphingosine , Structure determination , Structure–activity relationship , Mushroom , Grifola gargal , Osteoclast-forming suppressing
