Author/Authors :
Aneta M. Tomkiel، نويسنده , , Krzysztof Brzezinski، نويسنده , , Zenon ?otowski، نويسنده , , Leszek Siergiejczyk، نويسنده , , Piotr Wa?ejko، نويسنده , , Stanis?aw Witkowski، نويسنده , , Stefan Jan Kowalski، نويسنده , , Jolanta P?oszy?ska، نويسنده , , Andrzej Sobkowiak، نويسنده , , Jacek W. Morzycki، نويسنده ,
Abstract :
A new protocol for the electrochemical synthesis of glycoconjugates is presented. Thioether derivatives of cholesterol and other sterols were subjected to anodic oxidation in the presence of a sugar alcohol affording glycoconjugates with the sugar linked to a steroid moiety by an ether bond. The isomeric 6β-3α,5α-cyclo-steroidal thioethers proved to be better sterol donors than the normal 3β-Δ5-steroidal thioethers.
Keywords :
Glycosylation , cholesterol , Thioethers , Electrochemical oxidation , Glycoconjugates
