Title of article
A sort synthesis of polyhydroxylated pyrrolizidines via sequential 1,3-dipolar cycloaddition and reductive amination
Author/Authors
Petros Gkizis، نويسنده , , Nikolaos G. Argyropoulos، نويسنده , , Evdoxia Coutouli-Argyropoulou، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
8
From page
8921
To page
8928
Abstract
Polyhydroxylated pyrrolizidines bearing a methyl group at C-5 have been synthesized by 1,3-dipolar cycloaddition of five membered cyclic nitrones with methyl vinyl ketone followed by a N–O reductive cleavage and in situ intramolecular reductive amination. The stereochemistry of the obtained compounds is examined in relation to the reactions mechanism.
Keywords
Reductive amination , 1 , Azasugars , 3-dipolar cycloaddition , pyrrolizidines , Nitrones
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1106335
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