Title of article
The first iodine improved 1,3-dipolar cycloaddition: facile and novel synthesis of 2-substituted benzo[f]isoindole-4,9-diones
Author/Authors
Huan-ming Huang، نويسنده , , Jian-Rong Gao، نويسنده , , Lifen Hou، نويسنده , , Jian-Hong Jia، نويسنده , , Liang Han، نويسنده , , Qing Ye، نويسنده , , Yu-Jin Li، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
5
From page
9033
To page
9037
Abstract
The first novel protocol of the synthesis of 2-substituted benzo[f]isoindole-4,9-dione framework via the one-pot, 1,3-dipolar cycloaddition of quinones, paraformaldehyde and N-substituted amino ester hydrochlorides in the present of iodine at refluxing acetonitrile was reported. All these reactions proceed with good to excellent yields. The promising results obtained 1,3-dipolar cycloaddition will have the potential application in natural product exhibiting important biological activities.
Keywords
9-dione , 1 , Iodine , N-Substituted amino ester hydrochlorides , Quinones , 3-dipolar cycloaddition
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1106349
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