Title of article
A new class of phosphanucleosides containing a 3-hydroxy-1-hydroxymethylphospholane 1-oxide ring
Author/Authors
Ond?ej P?v، نويسنده , , Eva Zborn?kov?، نويسنده , , Milos Budesinsky، نويسنده , , Ivan Rosenberg، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
10
From page
9120
To page
9129
Abstract
Novel phosphanucleosides containing a 3-hydroxy-1-hydroxymethylphospholane 1-oxide ring were synthesized as compounds with potential biological activity. A double Arbuzov reaction was employed to prepare a phospholene precursor, which was then converted into an epoxide and subsequently into racemic phosphanucleoside via nucleobase construction.
Keywords
Nucleoside analogue , phospholane , conformation , Phosphanucleoside
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1106360
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