Title of article
Cascade reaction synthesis of multisubstituted bicyclic pyridone derivatives
Author/Authors
Xuebing Chen، نويسنده , , Dandan Zhu، نويسنده , , Xiaoying Wang، نويسنده , , Shengjiao Yan، نويسنده , , Jun Lin، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
13
From page
9224
To page
9236
Abstract
An efficient synthesis of novel bicyclic pyridone derivatives via cascade reaction of heterocyclic ketene aminals (HKAs) and 4-arylmethylene-2-phenyloxazol-5(4H)-ones in the presence of acetic acid has been established. Significantly, the protocol affords a straightforward approach to the construction of multisubstituted bicyclic pyridones in which one C–O bond was cleaved and new C–C and C–N bonds were formed in one pot under mild conditions.
Keywords
cascade reaction , 2-Phenyloxazol-5(4H)-ones , Bicyclic pyridones , Heterocyclic ketene aminals
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1106374
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