Title of article
Palladium-catalyzed one-pot synthesis of benzo[b][1,6]naphthyridines via Sonogashira coupling and annulation reactions from 2-chloroquinoline-3-carbonitriles
Author/Authors
Radhey M. Singh، نويسنده , , Ritush Kumar، نويسنده , , Neha Sharma، نويسنده , , Mrityunjaya Asthana، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
8
From page
9443
To page
9450
Abstract
Palladium-catalyzed one-pot synthesis of 1,3-disubstituted benzo[b][1,6]naphthyridines and [1,6]naphthyridines has been described from easily accessible precursors, 2-chloroquinoline-3-carbonitriles and 2-chloropyrido-3-carbonitrile via sequential additions of palladium-catalyst for Sonogashira-coupling and the following annulations in good to excellent yields. A plausible mechanism for annulation is discussed.
Keywords
1 , 6]naphthyridine , Palladium , One-pot , 2-Chloroquinoline-3-carbonitrile , Intramolecular
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1106399
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