Title of article
Sequential alkylation/cyclization/isomerization of ethyl 3-(o-trifluoroacetamidoaryl)-1-propargylic esters: a new route to 2-acyl- and 2-ethoxycarbonyl-3-alkenyl indoles
Author/Authors
Ilaria Ambrogio، نويسنده , , Antonio Arcadi، نويسنده , , Sandro Cacchi، نويسنده , , Giancarlo Fabrizi، نويسنده , , Antonella Goggiamani، نويسنده , , Fabio Marinelli، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
5
From page
9494
To page
9498
Abstract
The reaction of ethyl 3-(o-trifluoroacetamidoaryl)-1-propargylic esters with ethyl iodoacetate or α-bromoacetophenone in the presence of K2CO3 in DMSO provides a new simple access to 2-acyl- and 2-ethoxycarbonyl-3-alkenyl indoles.
Keywords
Propargylic carbonates , Indoles , sequential reactions , Cyclization , Intramolecular SN2?
Journal title
Tetrahedron
Serial Year
2013
Journal title
Tetrahedron
Record number
1106406
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