Title of article :
Voacalgines A–E, new indole alkaloids from Voacanga grandifolia
Author/Authors :
Yusuke Hirasawa، نويسنده , , Takashi Fujikawa and Hiroko Arai، نويسنده , , Abdul Rahman، نويسنده , , Idha Kusumawati، نويسنده , , Noor Cholies Zaini، نويسنده , , Osamu Shirota، نويسنده , , Hiroshi Morita، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2013
Abstract :
Five new indole alkaloids, voacalgines A–E (1–5) consisting of a C-mavacurine type of skeleton with 2,3-dihydroxybenzoate moiety, a macroline-type of skeleton, or a macroline-type of skeleton with C6 unit, were isolated from the bark of Voacanga grandifolia. Their relative structures were determined by means of NMR data. Voacalgine A showed moderate cell growth inhibitory activities against HL-60 and HCT116 cells.
Keywords :
indole alkaloid , Voacanga grandifolia , Voacalgine A , Cytotoxicity
Journal title :
Tetrahedron
Journal title :
Tetrahedron
