Title of article
A simple and highly efficient procedure for construction of quaternary carbons centers by tributylphosphine catalyzed bis-Michael addition
Author/Authors
Da-Zhen Xu، نويسنده , , Ming-Zhe Zhan، نويسنده , , You Huang، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
5
From page
176
To page
180
Abstract
The tributylphosphine-catalyzed bis-Michael addition reaction of various kinds of α,β-unsaturated carbonyl compounds with active methylenes is described. This is a convenient and rapid method for generating quaternary carbons centers and useful procedure for the synthesis of branched core and highly substituted trans cyclohexanones. All the reactions were completed in 60 min and afford the corresponding products in excellent yields.
Keywords
Michael addition , Quaternary carbons , Catalysis , Bis-adducts , Tributylphosphine
Journal title
Tetrahedron
Serial Year
2014
Journal title
Tetrahedron
Record number
1106628
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