Title of article
Cascade regioselective synthesis of pyrazoles from nitroallylic acetates and N-tosyl hydrazine
Author/Authors
Nana Shao، نويسنده , , Tong Chen، نويسنده , , Taotao Zhang، نويسنده , , Huajian Zhu، نويسنده , , Qunxiong Zheng، نويسنده , , Hongbin Zou، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
5
From page
795
To page
799
Abstract
A simple, practical, and regioselective synthetic protocol for the formation of pyrazoles was developed. Unlike all other previously reported reactions of nitroallylic acetates, this process was initiated by a SN2 reaction at the electrophilic γ site. A plausible mechanism for the cascade SN2-Michael synthesis is proposed.
Keywords
Michael addition , pyrazoles , N-Tosyl hydrazine , SN2 reaction , Nitroallylic acetates
Journal title
Tetrahedron
Serial Year
2014
Journal title
Tetrahedron
Record number
1106702
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