Title of article :
Peptidomimetics with tunable tertiary amide bond containing substituted β-proline and β-homoproline
Author/Authors :
Sandip Basu، نويسنده , , Pancham Singh Kandiyal، نويسنده , , Venkata Suresh Kumar Neelamraju، نويسنده , , Harjinder Singh، نويسنده , , Ravi Sankar Ampapathi، نويسنده , , Tushar Kanti Chakraborty، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
Tunable cis/trans prolyl amide bond configuration in substituted β-proline (β-Pro) and β-homoproline (β-Hpro) homodimers was explored, based on position and nature of the substituent. Tertiary amide bond in β-proline (β2,3-substituted) dimers show distinct trans configuration and β-homoproline (β3-substituted) dimers preferably exhibited cis configuration.
Keywords :
DFT , Peptidomimetics , ?-Proline and ?-homoproline , Cis–trans isomerization , 2D-NMR
Journal title :
Tetrahedron
Journal title :
Tetrahedron
