Title of article :
Efficient Solid-Phase Synthesis of 1,3,4-Trisubstituted (beta)-Thiolactams
Author/Authors :
Mendez، Luciana نويسنده , , Delpiccolo، Carina M. L. نويسنده , , Mata، Ernesto G. نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
An efficient solid-phase synthesis of a series of 1,3,4-trisubstituted (beta)thiolactams is described. The key reaction, a direct thionation of polymersupported (beta)-lactams, was carried out using the Lawesson’s reagent to give (beta)-thiolactams in good overall yields.
Keywords :
solid-phase synthesis , (beta)-thiolactams , Lawesson’s reagent , (beta)-lactams , combinatorial chemistry
