Title of article
Electrophilic Fluorination of 5-(Cyanomethyl)imidazole-4-carboxylate Nucleosides: Facile Entry to 3-Fluoro-3-deazaguanosine Analogues
Author/Authors
Sakthivel، Kandasamy نويسنده , , Cook، P. Dan نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-1585
From page
1586
To page
0
Abstract
A facile and efficient methodology is described for the synthesis of 3fluoro-3-deazaguanosines based on a novel electrophilic fluorination of 5(cyanomethyl)imidazole-4-carboxylate nucleosides. This general methodology can be readily applied to the synthesis of sugar-modified 3fluoro-3-deazaguanosine analogues.
Keywords
nucleosides , 3-deazapurine , 3-deazaguanosine , fluorinated nucleosides , electrophilic fluorination
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110703
Link To Document