Title of article :
Enantioselective Synthesis of Aliphatic Cyanohydrin Acetates
Author/Authors :
Veum، Lars نويسنده , , Hanefeld، Ulf نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
When the standard conditions for the enantioselective synthesis of cyanohydrin acetates via dynamic kinetic resolution are applied to aliphatic substrates, only a kinetic resolution is observed. However, by exchanging the base (Amberlite) against NaCN, quantitative conversions and good enantioselectivities are obtained.
Keywords :
Candida antarctica lipase B , enzyme catalysis , dynamic kinetic resolution , cyanohydrins , asymmetric synthesis
