Title of article
Efficient Enantioselective Total Synthesis of arabino-Phytosphingosine
Author/Authors
Jung، Doo Young نويسنده , , Kim، Yong Hae نويسنده , , Kang، Sol نويسنده , , Chang، Suk Bok نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
-2182
From page
2183
To page
0
Abstract
Enantioselective total synthesis of arabino-phytosphingosine has been achieved in 8 steps employing Claisen rearrangement and Fleming-Tamao oxidation as key steps. Installation of all chiral centers present in arabino-phytosphingosine was achieved through the use of asymmetric catalysis. This synthesis provides one of the most efficient routes to prepare 2amino-1,3,4-triol moiety.
Keywords
amino alcohol , enantioselective synthesis , total synthesis , sphingolipids , Claisen rearrangement
Journal title
Synlett
Serial Year
2005
Journal title
Synlett
Record number
110796
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