Title of article :
Highly Efficient Binary and Remote Asymmetric Induction from a Single Allyltin Reagent with a Chiral Carbamate Moiety
Author/Authors :
Nishigaichi، Yutaka نويسنده , , Takuwa، Akio نويسنده , , Ueda، Narifumi نويسنده , , Tamura، Ken-ichi نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
Carbamate-protected chiral allyltin reagent was found to afford either syn- or anti-homoallyl alcohol via 1,4-remote asymmetric induction in the reaction with various aldehydes depending on the applied Lewis acid, TiCl4-THF or SnCl4, respectively. The both stereocontrols were so effective that the selectivities higher than 90% were realized in most cases.
Keywords :
allylations , Lewis acids , protecting groups , Stereoselective synthesis , TIN
