Abstract :
The evolution of a synthetic approach to the challenging targets quassinoids is described. 1 Introduction 2 The Diels-Alder Reaction as a Key Feature 2.1 Intermolecular Diels-Alder 2.2 Intramolecular Diels-Alder 2.3 Unsuccessful Diels-Alder Cycloadditions 3 The Diene-Transmissive Approach to Quassinoids 3.1 Without the C10 Methyl Group 3.2 With the C10 Methyl Group 4 A Successful Sequence 5 Conclusion and Outlook
Keywords :
SN2´ displacement , vinylallenes , diene-transmissive Diels-Alder cycloaddition , Simaroubacea , quassinoids
