Title of article :
Pd-Catalyzed Cyclization of 1-Allyl-2-indolecarboxamides by Intramolecular Amidation of Unactivated Ethylenic Bond
Author/Authors :
Abbiati، Giorgio نويسنده , , Beccalli، Egle نويسنده , , Broggini، Gianluigi نويسنده , , Martinelli، Michela نويسنده , , Paladino، Giuseppe نويسنده ,
Abstract :
The intramolecular Pd(II)-mediated cyclization of 1-allyl-2-indolecarboxamides leads to pyrazino[1,2-a]indoles through the conversion of the olefinic C-H bond into a C-N bond by reaction with an amide group. When operating on the allylamide, a domino process was observed with a double C-H functionalization.
Keywords :
cyclizations , fused-ring systems , indoles , Palladium , domino reactions
Journal title :
Astroparticle Physics
