Title of article :
A Synthetic Approach to Sporotricale Methylether
Author/Authors :
Dallavalle، Sabrina نويسنده , , Nannei، Raffaella نويسنده , , Merlini، Lucio نويسنده , , Bava، Adriana نويسنده , , Nasini، Gianluca نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
A synthetic approach to sporotricale methylether, a metabolite of the fungus Sporotrichum laxum with inhibitory activity against Helicobacter pylori, is described. The synthesis relies on the condensation of 13-hydroxy-10-oxotetradecanal, prepared via reaction of a sulfone-activated moiety with valerolactone, with diethyl 3,5-dimethoxyphthalide-7-phosphonate.
Keywords :
total synthesis , sulfones , hydrogenation , condensation , natural products
