Title of article
Efficient Enantioselective Synthesis of (alpha)-Hydroxy-?-amino Acids Using the Claisen and Curtius Rearrangements
Author/Authors
Chang، Sukbok نويسنده , , Jung، Doo Young نويسنده , , Kim، Yong Hae نويسنده , , Kang، Sol نويسنده ,
Pages
-85
From page
86
To page
0
Abstract
Highly enantioselective and facile synthesis of (alpha)-hydroxy-?-amino acids has been achieved using the Claisen and Curtius rearrangements as key reactions. Chiral allylic alcohols were employed, which can be prepared by asymmetric catalysis in both E- and Z-forms; both anti- and syn-(alpha)-hydroxy-?-amino acids have been synthesized.
Keywords
enantioselective synthesis , amino acids , Curtius rearrangement , Claisen rearrangement , amino alcohols
Journal title
Astroparticle Physics
Record number
110902
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