Title of article :
Three-Component Friedel-Crafts Reaction of Indoles, Glyoxylate, and Amine under Solvent-Free and Catalyst-Free Conditions - Synthesis of (3-Indolyl)glycine Derivatives
Author/Authors :
Wang، Dong نويسنده , , Liu، Li نويسنده , , Chen، Yong-Jun نويسنده , , Zhao، Jun-Ling نويسنده , , Zhang، Hai-Bo نويسنده , , Wu، Yan-Chao نويسنده ,
Abstract :
Solvent-free and catalyst-free three-component reactions of indoles, amines, and ethyl glyoxylate gave alkylation products in good to high yields (61-93%), providing a convenient synthesis of (3-indolyl)glycine derivatives.
Keywords :
solvent-free , Indole , catalyst-free , three-component alkylation , Amine
Journal title :
Astroparticle Physics
