Title of article :
A General Thiolation of Magnesium Organometallics Using Tetramethylthiuram Disulfide
Author/Authors :
Krasovskiy، Arkady نويسنده , , Knochel، Paul نويسنده , , Gavryushin، Andrey نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
The reaction of various functionalized aryl and heteroaryl bromides with i-PrMgCl·LiCl produces highly reactive Grignard reagents complexed by LiCl, which react with tetramethylthiuram disulfide [(Me2NCS2)2] leading to the corresponding dithiocarbamates in excellent yields. Various transformations of the dithiocarbamates to thiols, thiol salts or thioethers have been demonstrated.
Keywords :
sulfur , lithium chloride , tetramethylthiuram disulfide , Chirality , Grignard reactions
